肠淋巴液对大鼠血压的影响

EFFECT OF INTESTINAL LYMPH ON BLOOD PRESSURE OF RAT

本文用引流及输入肠淋巴液的方法，研究了畅淋巴液对大鼠血压的影响。结果如下：（1）经肠淋巴管插管引流肠淋巴液的大鼠，自引流后150min起，血压显著低于假手术组（P＜0．05）。（2）在丢失肠淋巴液同时，补充等量白蛋白或脂肪乳。仍不能防止血压下降，但肠淋巴管-颈静脉搭桥大鼠，在4h观察过程中，血压不出现见著降低。（3）重症失血性休克大鼠输入小量肠淋巴液后，血压显著回升，其血压水平及存活时间显著优于对照组（P＜0.05～0．01）。上述结果表明，淋巴系统除了已知的组织液回流途径及维持血容量等功能外，肠淋巴液可能还具有维持血压的重要作用。

The effect of intestinal lymph on blood pressure in rats was observed by the methods of lymph drainage and lymph infusion. The results obtained are as follows: (1) Afte r 150 min of the lymph drained through the cannula of intestinal lymph duct, theblood pressure was significantly lower than that of the sham group (P＜0. 05). (2) Equivalent albumin or intralipid infusion was not able to prevent the decrease in bloodpressure when the lymph was lost. But in jugular-intestinal lymph duct shunt group,no significant blood pressure decrease could be seen during the drainage procedure for 4h.(3) The blood pressure of rat with serious hemorrhagic shock could be increased significantly with a little amount of intestinal lymph infusion, and the rats survived longerthan those of the control group (P＜0. 05~0. 01 ). The above results suggest that theintestinal lymph may play an important role in maintenance of blood pressure, in addition to the known function of lymphatic system by returning tissue fluid to blood andmaintaining circulating blood volume.