成都地区无偿献血者血小板数量调查

INVESTIGATION OF PLATELET COUNT OF BLOOD DONORS IN CHENGDU

[目的]调查成都地区献血者血小板数量参数,帮助血小板献血者的招募。[方法]采用血清学流行病学方法对献血者血液标本在24h内用血细胞分析仪测定血小板计数。[结果]成都地区献血者以青壮年为主,18～29岁占71.6%,30～39岁占20.6%,40岁以上占7.8%。女性血小板数明显高于男性(P<0.001);年龄增加血小板数下降。血小板均数和标准差:男性,(153±53)×109/L;女性,(167±58)×109/L。血小板数≥150×109/L的概率,18～29岁男性为56%、女性为67%;30～39岁为45%;40～55岁为40%。影响男性血小板数的明显因素为脂质与素食饮食(P<0.038),肥胖(BMI≥24kg/m2)与消瘦(BMI<18.5kg/m2=(P<0.036);体力与脑力劳动对女性血小板数量有显著影响(P=0.017);其他因素,如血型、居住等,对献血者血小板数无明显影响。[结论]该地区献血者血小板数量低于国内平均水平。血小板数量的影响因素需进一步调查。

[Objective] To investigate the platelet count of blood donors in Chengdu and help recruit blood donors for platelet donation. [Methods] The number of platelet of blood donors was counted by cytoanalyze in 24 hours. [Results] The main blood donors in Chengdu were young people. The donors at the age of 18-29 accounted for 71.6%. 30-39 about 20.6%, above 40 about 7.8%. The female platelet count was obvious higher than male （P 〈 0.001 ） in general. The platelet count decreased while donors grew older. The mean and standard deviation of platelet were： male, （153 ±53）×10^9/L; female, （167 ±58）×10^9/L; the probabilities of platelet count more than 150×10^9/L were 56% for male and 67% for female at age of 18-29; about 45% for all at age of 30-39, and 40% for all at age of 40-55. The obvious influencing factors for male were meat versus vegetable food （P 〈 0.038）, obesity （ BMI≥24kg/m^2） and emaciation （ BMI〈 18.5kg/m^2） （P 〈 0.036）. But it was different for female, the obvious influencing factor was brainwork and manual work （P = 0.017）. The other factors, such as ABO blood group, inhabitation condition and so on, did not obviously influence the platelet count of blood donors. [ Conclusion] The platelet count of blood donors in Chengdu is less than the average platelet count of people in other areas of China. The factors that influence the number of platelet of blood donors need a further investigation.