两个萘并呋喃类分子探针与A β结合的计算机模拟研究

Computer-based Simulation of the Binding between Two Imaging Agents of Naphthofuran and β-Amyloid

应用MVD2007软件对两个萘并呋喃类分子探针与Aβ的分子对接过程进行了模拟,得出MNF与Aβ的结合能力优于NFB与Aβ的结合能力。

MVD2007 is used in simulating the molecular docking process between two imaging agents of naphthofuran and β-amyloid. From the result we conclude that the binding ability between A β and MNF is better than that between A β and NFB.