自体脂肪颗粒注射移植治疗哺乳后乳腺萎缩的临床评价

CLINICAL EVALUATION OF EFFECT OF TRANSPLANTATION BY AUTO-FAT GRANULE INJECTION FOR MASTATROPHY POST SUCKLING

目的总结自体脂肪颗粒注射移植治疗哺乳后乳腺萎缩的临床效果。方法 2000年3月-2006 年6月,收治73例146侧哺乳后乳腺萎缩者。年龄28～52岁,平均37岁。哺乳停止后2～10年,乳房逐渐萎缩、变小,弹性下降。采用注射器抽吸腹、腰、臀、大腿及背部脂肪颗粒,经反复冲洗、纯化后注射移植于乳腺后间隙,每次单侧注射50～100 mL,间隔3～6个月,共2～6次。结果 73例患者术后切口均Ⅰ期愈合,其中 65例获随访6个月～3年。乳房大小和外形均明显改善,质地柔软,手感好,形态自然;形体曲线更美,自信心增强,焦虑、忧郁心理缓解,生活质量提高。 7例10侧乳房于首次术后2～7个月出现散在小硬结,5例8侧乳房于首次术后9～14个月出现散在小钙化灶,均未作特殊处理。结论自体脂肪颗粒注射移植治疗哺乳后乳腺萎缩效果满意,是一种切实可行的治疗方法。

Objective To investigate the clinical effect of transplanting by auto-fat granule injection for mastatrophy post suckling. Methods From March 2000 to June 2006, 73 patients（146 breasts ） with mastatrophy post suckling were treated by transplanting auto-fat granule. The mastatrophy occurred between ages 28 and 52 years with a median of 37 years post suckling. The breasts shrank and their elasticity decreased gradually within 2-10 years post suckling. The auto-fat granule was obtained by liposuction with syringe from patient＇s abdomen, waist, buttocks and thighs, etc. After repeated wash and purification, the auto-fat granule was transplanted into the interspace behind the breast by injection. The quantity of auto-fat granule was 50-100 mL in each side of breast per transplantation at 3-6 months intervals, and the whole course of treatment needed 2-6 transplantations. Results The incisions in all cases healed primarily postoperatively. In 73 cases, 65 were followed up from 6 months to 3 years post operation. All patients had a significant improvement in their breast size and shape postoperatively and their breasts were soft and natural in appearance and feel. All of them had more perfect arcuation of physique and body with strengthened self-confidence, relieved mood and improved quality of life. However, small indurations were found sporadically in 7 cases （10 breasts） within 2-7 months, and calcifications in 5 cases （8 breasts） within 9-14 months post the first operation. Condusion The transplantation by auto-fat granule injection for mastatrophy post suckling is an effective and practical method. The surgical technique is well worth performing in clinical practice.