摘要
防突变浓度(MPC)及突变选择窗(MSW)是由ZhaoX等近几年提出的防耐药变异的新概念。结合文献,本文对MPC及MSW几个相关问题进行了探讨,并简单综述了抗菌药物防耐药变异应用策略。
The mutant prevention concentration (MPC) and mutant selective window (MSW) were new conceptive theories of resistance mutantion preventation which were raised by Zhao X and Drlica K et al. In this paper, the conceptions of MPC and MSW and some could related issues were discussed. Finally how to prevent resistance mutantion was reviewed.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2008年第1期21-24,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
防突变浓度
突变选择窗
最低抑菌浓度
耐药变异
mutant prevention concentration
mutant selective window
minimum inhibitory concentration
resistance mutantion