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国产盐酸吡格列酮对2型糖尿病患者CRP、IL-6的影响 被引量:5

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摘要 目的:研究国产盐酸吡格列酮对2型糖尿病患者CRP、IL-6的影响。方法:将50例确诊的2型糖尿病患者,随机分为二甲双胍组和吡格列酮组,观察两组治疗前后血清C反应蛋白、白介素-6及空腹胰岛素抵抗指数、空腹血糖等指标的变化。结果:治疗12周后,两组患者空腹血糖均显著降低;C反应蛋白、白介素-6、空腹胰岛素抵抗指数等指标仅在吡格列酮组降低,与二甲双胍组比较差异有统计学意义(P<0.05)。结论:盐酸吡格列酮可降低2型糖尿病患者C反应蛋白、白介素-6水平。
出处 《实用诊断与治疗杂志》 2008年第3期215-216,共2页 Journal of Practical Diagnosis and Therapy
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