摘要
蛋白质组学是独立于基因组学而发展起来的一门新兴前沿学科,是在特定的时间和空间研究一个完整生物体(或细胞)所表达的全体蛋白质的特征,从而在蛋白质水平上全面认识有关生物体生理、病理等过程。该文综述了蛋白质组学研究的双向电泳、生物质谱、生物信息学等技术及其在弓形虫研究中的应用。
Proteomics is a new emerging frontier of science independent of genomics that research the characteristics of all protein expressions of an intact organism ( or cells) , thus to obtain a comprehensive knowledge of physiological and pathologic process at protein level. In this paper, the key technology of proteomics research including two-dimensional electrophoresis, bio-mass spectrometry and bioinformatics as well as its application in research on Toxoplasma gondii were reviewed.
出处
《国际医学寄生虫病杂志》
CAS
2008年第1期29-32,共4页
International JOurnal of Medical Parasitic Diseases
基金
国家自然科学基金(30640057)
山西省自然科学基金(20041105)
关键词
蛋白质组学
双向电泳
生物质谱
弓形虫
Proteomics
Two-dimensional gel electrophoresis
Mass spectrometry
Toxoplasma gondii