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内皮素与蛛网膜下腔出血后脑血管痉挛 被引量：1

Endothelin and Cerebral Vasospasm Following Subarachnoid Hemorrhage
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摘要 蛛网膜下腔出血（SAH）后脑血管痉挛（CVS）是脑动脉瘤患者死亡和残疾的主要原因之一。内皮素（ET）在SAH后CVS的发生中起着重要作用。文章从基础和临床两个方面阐述了ET在CVS中的作用，并就针对ET治疗CVS的前景做了展望。 Cerebral vasospasm （CVS） following subarachnoid hemorrhage （SAH） is one of the leading causes of death and disability in patients with intracranial aneurysms. Endothelin （ET） plays important a role in the occurrence of CVS following SAH. This article expounds the effect of ET on CVS both from clinical and basic aspects, and it also prospects the treatment of CVS targeted ET.
作者 裴圣林 王均炉
机构地区 温州医学院附属第一医院麻醉科
出处 《国际脑血管病杂志》 2008年第1期63-67,共5页 International Journal of Cerebrovascular Diseases
关键词 内皮素 脑血管痉挛 蛛网膜下腔出血 内皮素受体 信号转导 内皮素受体拮抗剂 内皮素转换酶抑制剂 endothelin cerebral vasospasm subarachnoid hemorrhage endothelin receptor signal transduction endothelin receptor antagonist endothelin converting enzyme inhibitor
分类号 R743.35 [医药卫生—神经病学与精神病学] R544.1 [医药卫生—心血管疾病]
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参考文献33

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同被引文献23

  • 1Beck J, Raabe A. Clazosentan: prevention of cerebral vasospasm and the potential to overcome infarction. Acta Neurochir Suppl, 2011, 110: 147-150.
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国际脑血管病杂志
2008年 第1期

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