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马鞍山地区铜绿假单胞菌感染与耐药分析

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摘要 目的了解马鞍山地区铜绿假单胞菌感染情况及耐药性,为临床合理应用抗茵药物提供依据。方法对我院2005年1月~2006年12月从临床标本中分离出的396株铜绿假单胞菌,利用美国Microscan walk away40型全自动细菌鉴定分析系统进行鉴定,并采用MIC法对分离出的铜绿假单菌选用15种抗菌药物进行敏感性测定。结果铜绿假单胞菌保持抗菌活性较强而耐药低于30%的抗菌药物有阿米卡星、头孢吡肟、头孢哌酮等,对哌拉西林/他唑巴坦、环丙沙星、头孢他啶、亚胺培南等主要抗菌药物的耐药率有普遍上升的趋势。感染部位依次为呼吸道、伤口、血液、胆汁等。结论铜绿假单胞菌存在较严重的交叉耐药及多重耐药现象。应加强对铜绿假单胞菌的耐药性监测,规范抗菌药物的应用,及早进行菌株培养和药敏,是控制铜绿假单胞菌感染和耐药上升的有效措施。
作者 顾娟
出处 《淮海医药》 CAS 2008年第2期149-150,共2页 Journal of Huaihai Medicine
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