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危重病患者应该输注白蛋白吗？ 被引量：3

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摘要 危重病患者是否应该输注人血白蛋白已经激烈争论了很多年，主要源于人血白蛋白对疾病预后和器官功能的影响，另外昂贵的价格和供给困难等也是影响白蛋白（albumin）应用的重要因素。正常人体内白蛋白具有维持血浆渗透压、物质结合和运输以及抗氧化和清除自由基等作用，但是在严重的疾病状态下，
作者 赵聪 马晓春
机构地区 中国医科大学附属第一医院重症医学科
出处 《中国危重病急救医学》 CAS CSCD 北大核心 2008年第3期187-190,F0003,共5页 Chinese Critical Care Medicine
关键词 危重病 白蛋白 治疗
分类号 R459.7 [医药卫生—急诊医学]
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参考文献58

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同被引文献43

  • 1尹明,李银平.危重病中白蛋白的应用——两难中的选择[J].中国危重病急救医学,2006,18(10):637-640. 被引量：21
  • 2Dellinger RP,Levy MM,Carlet JM,et al. Surviving Sepsis Campaign:international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med, 2008,34:17-60.
  • 3Peake S, Webb S, Delaney A. Early goal-directed therapy of septic shock : we honestly remain skeptical. Crit Care Med,2007,35 : 994-995.
  • 4Puskarich MA, Marchiek MR, Kline JA, et al. One year mortality of patients treated with an emergency department based early goal directed therapy protocol for severe sepsis and septic shock: a before and after study. Crit Czre, 2009,13 : R167.
  • 5Finfer S,Bellomo R,Boyce N,et al. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med, 2004,350: 2247-2256.
  • 6Haynes GR, Navickis R J, Wilkes MM. Albumin administration: what is the evidence of chnical benefit ? A systematic review of randomized controlled trims. Eur J Anaesthesiol,2003,20: 771-793.
  • 7Perel P ,Roberts I. Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database of Systematic Reviews, 2011 http://onlinelibrary, wiley, corn / doi / 10. 1002 / 14651858. CD000567. pub4/full.
  • 8Bunn F,Trivedi D,Ashraf S. Colloid solutions for fluid resuscitation. Cochrane Database of Systematic Reviews, 2011, http://onlinelibrary, wiley, com/doi/10. 1002/14651858. CD001319. pub3/full.
  • 9Boldt J, Heesen M, Mfiller M, et al. The effects of albumin versus hydroxyethyl starch solution on cardiorespiratory and circulatory variables in critically ill patients. Anesth Analg, 1996,83:254- 261.
  • 10Boldt J, Heesen M, Wehers l,et al. Does the type of volume therapy influence endothelial-related coagulation in the critically ill? Br J Anaesth, 1995, 75 : 740-746.

引证文献3

二级引证文献19

中国危重病急救医学
2008年 第3期

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