豚鼠组织中缩醛磷脂酰乙醇胺生物合成能力的比较

Biosynthesis power of phosphatidal- ethanolamine in guinea pig tissues

目的:探讨豚鼠不同组织中缩醛磷脂酰乙醇胺生物合成能力及其生理意义。方法:使用[3H]-乙醇胺作为原料物,经腹膜内注射至豚鼠体内,检查该标记物在含乙醇胺的缩醛磷脂中在不同组织内的合成能力。结果:显示标记乙醇胺进入缩醛磷脂的能力具有组织特异性,在心脏和大脑中合成能力最强,分别占41%和40%,肾脏居中,占25%。合成能力最低的是肝脏,仅占9%。结论:心脏和大脑是合成缩醛磷脂酰乙醇胺的主要器官,这与它们的重要生理功能相吻合。

Objective ：To approach the biosynthesis power of phosphatidat-ethanolamine in guinea pig tissues for physiological studies. Mahods ：Experimental guinea pigs were injected interperitoneally with [^3H]-ethanolamine for exploring biosynthesis power by detecting phosphatidal-ethanolamine-contained label in different tissues. Results：The results revealed that labeling ethanolamine into phosphatidalethanolamine demonstrated specificity in tissues. The biosynthesis power in heart and brain was prominent （41% and 40% respectively） and followed by kidney tissues （25 % ）, less power was seen in liver tissues with a percentage of 9%. Conclusion ：The heart and brain were central organs in biosynthesis of phosphatidal-ethanolamine, which is identical with their important physiological function.