摘要
目的:探讨黑斑息肉病(Peutz-Jeghers综合征,PJS)的临床特征、诊断及治疗。方法:统计2000-2005年收治的黑斑息肉病患者9例,对其临床表现及治疗对策进行分析。结果:内镜检查发现9例均有结、直肠息肉;小肠造影提示2例同时伴有胃和小肠息肉,4例伴小肠息肉;病理检查均为错构瘤;其中1例患者出现癌变,2例患者合并有腺瘤;2cm以下息肉在内镜下分批行电凝、电切治疗,1例癌变转外科手术。结论:内镜治疗对PJS疗效满意,同时鉴于PJS与恶性肿瘤密切相关,长期监测、定期复查有利于恶性病变的早期发现与治疗。
Objective:To investigate the clinical manifestation of Peutz- Jeghers' syndrome for diagnosis and treatment. Methods : The data of 9 patients confirmed with PJS from 2000 to 2005 in our hospital were collected for this retraspective study in terms of clinical features, diagnosis and treatment. Results: Endoscopic findings suggested that polyps of colorecturn were seen in 9 patients, in which 2 casecs were confirmed by visualization with gastric polyps and bowd polyps, and 4 cases with small bowel polyps. Pathological findings showed that the total 9 cases presented with hamartomas, in which 1 case was in presence of canceration and 2 cases were complicated with adenomatous polyps. Polyps of less 2 cm in diameter were undergone high frequency electro-coagulation or electro-resection by endoscopy and another 1 canccration case was referred to surgical operation. Conclusion : Endoscopic therapy is sound to Peutz-Jeghers syndrome, but patients should be followed up and Examined regularly for early discovery and treatment since the disease may precede canceration.
出处
《皖南医学院学报》
CAS
2008年第1期46-47,共2页
Journal of Wannan Medical College
关键词
P-J综合征
诊断
治疗
Peutz-Jeghers Syndrome
diagnosis
treatment