甲亢患者治疗前后血清FT_3、FT_4和S IL-2R水平的变化及临床意义

Clinical Significance of Changes of Serum FT_3,FT_4 and SIL-2R Levels After Treatment in Patients with Hyperthyroidism

目的:探讨了甲亢患者治疗前后血清FT3、FT4和SIL-2R水平的变化及临床意义。方法:分别应用放免法和酶联免疫法对55例甲亢患者进行了治疗前后血清FT3、FT4和SIL-2R水平的变化观察,并与35名正常健康人作比较。结果:治疗前血清FT3、FT4和SIL-2R水平非常显著地高于正常人组(P<0.01),经治疗后3个月则与正常人比较无显著性差异(P>0.05),血清SIL-2R水平与FT3、FT4呈明显正相关(r=0.6018、0.6117,P<0.01)。结论:检测甲亢患者血清FT3、FT4和SIL-2R水平的变化,对观察疗效和预后判断有一定的临床使用价值。

Objective To explore the clinical significance of changes of serum FT3, FT4, SIL -2R levels after treatment in padents with hyperthyroidism. Methods Serum FT3, F4, TSH （with R/A） and SIL -2R （with ELISA） levels were measured in 55 patients with hyperthyroidism both before and after treatment as well as in 35 controls. Results Before treatment, in the patients the serum FT3 FT4, SIL - 2R levels were significantly higher than those in the controls （ P 〈 0.01 ）. After treatment for 3 months the serum FT3, FT4, SIL - 2 levels were not significantly different from those in controls （ P 〉 0.05 ）. Conclusion Detection of serum FT3,FT4, SIL - 2R levels is valuable for treatment outcome prediction in patients with hyperthyroidism.