2005年山西省健康人群流行性脑脊髓膜炎免疫水平和带菌状况调查

Investigation on Immune Level Against Epidemic Cerebrospinal Meningitis and Carrier Status among Healthy Population in Shanxi

[目的]了解健康人群流行性脑脊髓膜炎(流脑)带菌状况和免疫水平,为流脑的防控提供依据。[方法]2005年3月,在山西省选择方山县、襄汾县、寿阳县、晋城市城区、大同市南郊区,采集7个年龄组健康人群咽拭子及静脉血,分别进行培养及血清抗体检测。[结果]检测919人,咽拭子脑膜炎奈瑟菌阳性的11份,带菌率为1.20%。其中,A群菌阳性带菌率为0.65%,B群菌带菌率为0.54%;血清抗体阳性率,A群为23.39%,C群为10.34%。[结论]山西省健康人群流脑带菌率不高,A群、C群流脑抗体阳性率较低。

[Objective]To understand the immune level against epidemic cerebrospinal meningitis and carrier status of neisseria meningitidis in healthy population,provide scientific basis for prevention and control. [Methods]Blood specimens and throat swab were collected from the people in 7 different aged groups from Fangshan,Xiangfen and Shouyang Counties,the suburb of Jingcheng and the suburban district of Datong, cultured and antibody was tested. [Results]Of the 919 people tested for Neisseria meningitides of throat swab, 11 were positive,accounting for 1.20 Y0. The positive rate of group A Neisseria meningitidis was 0. 65 %. The positive rate of group B Neisseria meningitidis was 0.54 %. The positive rate of serum antibody against Group A and Group C was 23, 39% and 10.34% respectively. [Conclusion] The carrier rate of Neisseria meningitidis in healthy population is relatively low and the antibody level against Group A and C meningococci in Shanxi Province is relatively low.