2005～2006年莱芜市部分狂犬病疫苗接种者狂犬病抗体检测

Examination of Rabies Antibody after Vaccination in Laiwu City from 2005 to 2006

[目的]了解狂犬疫苗接种后抗体的产生情况，掌握疫苗接种后的自身免疫状况，指导狂犬病防治工作。[方法]随机抽取2005-2006年莱芜市狂犬疫苗接种者725人，应用酶联免疫试验，检测狂犬病毒中和抗体。[结果]．3725例犬咬伤患者进行狂犬抗体检测273人，其中抗体阳性者236人，阳性率为86．45％。农民、工人、干部三类人群抗体阳性率分别为87．10％，88．78％，84．07％。[结论]疫苗接种后抗体阳性率并非100．00％，必须进行狂犬抗体的检测，阴性人群必须进行加强免疫，以确保抗体的产生。

[Objective]To understand rabies antibody and the status of autoimmunity after vaccination , provide scientific basis for rabies control and prevention. EMethods3725 vaccinated persons from 2005 to 2006 in Laiwu city were randomly selected,neutralizing antibody against rabies virus was tested with ELISA. [Results]Of the 725 cases bitten by dogs, 273 cases were tested for rabies antibody. 236 cases were positive for rabies antibody, accounting for 86.45%. The positive rate was 87. 10 %, 88. 78 % and 84.07 % respectively in peasants, workers and government employees. [Conclusion]The positive rate after vaccination can＇t reach to 100.00 %, examination of rabies antibody must be conducted, booster dose must be given to the persons with negative result to ensure the producing of antibody.