妊娠期糖尿病血糖控制水平对母婴结局的影响

Impact of different blood glucose levels in gestational diabetes mellitus on maternal and neonatal outcomes

目的:探讨妊娠期糖尿病血糖控制水平对妊娠母婴结局的影响。方法:回顾性分析2001年1月～2006年10月住院分娩的65例妊娠期糖尿病患者,其中46例在诊断妊娠期糖尿病后,血糖一直控制达标,19例血糖控制未达标,将两组的妊娠结局进行比较。结果:妊娠期糖尿病血糖控制未达标组中妊娠期高血压、胎膜早破、羊水过多、产后出血、早产儿、新生儿窒息、巨大儿、34周以后接受治疗者分别为42.11%,26.32%,31.58%,21.05%,47.37%,15.79%,36.84%,57.89%均明显高于妊娠期糖尿病血糖控制已达标组,分别为15.22%,4.35%,6.52%,2.17%,17.39%,0.00%,10.87%,28.26%。结论:妊娠期糖尿病对母婴危害大。及早诊断和治疗,可减少母婴并发症。

Objective：To evaluate the impact of different glucose levels in women with gestational diabetes mellitus on maternal and neonatal outcomes. Methods：Data of 65 pregnant women with GDM admitted in our hospital from January 2001 to October 2006 were reviewed. A total of 46 GDM women had blood glucose levels under control before delivery and the rest 19 GDM women did not. The impact of different glucose levels on maternal and neonatal outcomes were compared between the two groups. Results：In the group with the glucose level uncontrolled,the incidence of hypertensive disorder complicating pregnancy, premature rupture of membrane,hydramnios,postpartum hemorrhage, premature infant,neonatal asphyxia,fetal macrosomia,and therapy after 34 weeks pregnancy were 42.11%, 26.32%, 31.58%, 21.05%, 47.37%, 15.79%, 36.84%, and 57.89%, respectively. compared with those of the group with glucose level controlled as 15.22%,4.35%,6.52%,2.17%,17.39%,0.00%,10.87%,and 28.26% ,respectively.All the rates of the uncontrolled group were markedly higher than those of the controlled group. Conclusion：Gestational diabetes mellitus does great harm to mother and infant. Diagnosing GDM and controlling blood glucose as early as possible can decrease the complications of mother and infant.