巨大儿的影响因素分析

The study on large for date infant and its interrelated factors

目的:应用描述性研究的方法,找出巨大儿的危险因素,为避免巨大儿的发生和为优生优育提供可靠的理论依据。方法:符合纳入和排除标准的5842例确立为分析和研究的对象。结果:①巨大儿的影响因素单因素非条件Logistic回归结果发现:体块指数、产前空腹血糖、产前血压、新生儿性别、胎盘重量对巨大儿有影响(P<0.05),其中产前高血糖及男孩是危险因素,发生巨大儿的机率大,产前高血压及女孩是保护因素,发生巨大儿的机率小;②巨大儿多因素非条件Logistic回归结果发现:产前血糖、胎盘重量及新生儿性别有统计学意义(P<0.05),其中产前血糖、胎盘重量是危险因素,新生儿性别是保护因素。结论:产前空腹血糖、新生儿性别及胎盘重量和巨大儿的发生有关。

Objective： Through the method of the case - control study, find the influencing factors of large for date infant, and provide the convincing theoretical evidence for avoiding the occurrence of large for date infant and realizing eugenics. Methods： 5 842 infants conformed to the entering and excluding standard were selected as the objective of analysis and study. Results： ① Single factor non - condi- tional Logistic regression of large for date infant concluded that body mass index, prenatal fasting blood glucose, prenatal blood pressure and neonatal sex, placental weight all had influence on large for date infant （ P 〈 0. 05 ） , prenatal hyperglycemia and boys were risk factors and the incidence of large for date infant was high, while prenatal hypertension and girls were protective factors and the incidence of large for date infant was low. ② Multiplicity non - conditional Logistic regression of large for date infant concluded that prenatal blood glucose, placental weight and neonatal gender had the statistic significance （P 〈 0.05） . Among them, prenatal blood glucose and placental weight were risk factors, and neonatal gender was protective factor. Conclusion： Prenatal fasting blood glucose, neonatal gender and placental weight are related to the occurrence of large for date infant.