46例儿童咳嗽变异性哮喘的呼吸阻抗肺功能测定及过敏原检测分析

Measurement of respiratory impedance & pulmonary functions and analysis of allergen on 46 children patients with cough variant asthma

目的:探讨儿童咳嗽变异性哮喘(CVA)的肺功能特征及过敏原检测结果的特征。方法:选择46例儿童CVA患者作为研究组,同时选取同期就诊的急性支气管炎患儿25例作为对照组,两组患儿同时进行了呼吸阻抗肺功能检测及过敏原皮肤点刺检测,另外对于气道阻力增高者加做支气管舒张试验。结果:CVA患儿均存在气道阻力不同程度的增高,其阻力增高程度与对照组相比有显著差异,气道阻力增高者舒张试验阳性率为75%,CVA组过敏原检测的阳性率与急性支气管炎组相比较有显著差异。结论:CVA患儿大部分有可逆性气道阻塞,并且其发病与过敏因素关系密切,因此对长期慢性咳嗽患儿进行肺功能检测及过敏原检测有助于明确病因诊断。

Objective： To discuss and assess the characteristics of pulmonary functions and the characteristics of test result of allergen in children patients with cough variant asthma （CVA） . Methods： Selected 46 children cases with CVA as the study group and 25 children cases with acute bronchitis as the control group. The two groups of children were given the pulmonary function test for respiratory imped-ance and the skin prick test for analysis of allergen. Bronchial dilatation test was also performed on patients with airway resistance increase. Results： The test showed that the airway resistance of CVA patients had increased at different levels, and there was an obvious difference compared with the cases from the control group. The positive percentage of patients who had airway resistance increase was 75% shown in the bronchial dilatation test. The positive percentage in the allergen test was greatly different from the control group. Conclusion： Most CVA children patients may have the reversible airway obstruction which is greatly in relation to the allergic factors. Therefore, it will help and benefit the definite diagnosis by conducting the pulmonary function test and the allergen test.