溃疡性结肠炎患者发生异型增生的诊治研究

Study of the dysplasia in patients with ulcer conlitis

目的探讨对存在异型增生的溃疡性结肠炎患者合理的诊治方法。方法回顾2000年～2005年我院溃疡性结肠炎患者的临床资料,并对接受结肠镜下治疗的患者进行复查和随访。结果收集溃疡性结肠炎患者共计353例,有39例存在平坦型异型增生;在76例存在隆起性病变的患者中,21例存在异型增生。异型增生经结肠镜下电灼切除或氩离子凝固法治疗后,复查、随访至今尚无恶性病变发生。结论结肠镜下活检和治疗是存在异型增生的溃疡性结肠炎患者理想的手段。

Objective To decrease the incidence of colorectal cancer from dysplasia in patients with ulcer conlitis. Method Review the clinical data of the patients with ulcer conlitis in our hospital from 2000 to 2005. And follow up the patients who had been underwent the endoscopic treatment. Result There were 353 cases of ulcer conlitis ,39 cases of them had flat dysplasia. In the 76 patients who had elevated foci, there were 21 cases had dysplasia. All the dysplasia foci were treated by endoscopic resection or argon plasma coagulation,and no colorectal cancer were found until now. Conclusion Endoscopic biopsy and treatment are helpful to prevent the dysplasia cancerization for the patients with ulcer conlitis,