甲亢性心脏病左心室重量指数与左心功能的关系

Study on correlation between Left ventrical mass index and left ventricular function in thyrotoxic heart disease

目的探讨甲状腺功能亢进性心脏病(甲亢性心脏病)患者左心室(左室)重量指数与左心功能的关系。方法彩色多普勒超声心动图检测35例甲亢性心脏病患者左室舒张末期内径(LV),舒张末期左室后壁厚度(IVS)和室间隔的厚度(LVPW);收缩末期左心房横径(LA);测量左室舒张早期(E峰)和舒张晚期(A峰)二尖瓣最大血流速度。计算左心室重量指数(LVMI)和舒张早晚期的最大血流速度比值(E/A),并与30名正常人(对照组)比较。结果甲亢性心脏病患者LVMI高于对照组,两组比较差异有非常显著性(t=6.23,P<0.01);二尖瓣血流频谱E/A比值明显低于对照组(t=6.39,P<0.01);LVMI与E/A比值之间存在显著负相关(r=-0.79,P<0.01)。结论LVMI结合二尖瓣血流频谱E/A比值可早期诊断和评估甲亢性心脏病的左心功能。

Objective To investigate the relationship between Left ventrical mass index （LVMI） and left ventricular function in thyrotoxic heart disease. Methods Thirty-five patients with thyrotoxic heart disease and thirty normal controls were studied. LVMI and the peak value of mitral annular early diastolic velocity （E） and late diastolic velocity （A） were measured with Doppler echocardiography. Results LVMI was significantly higher in the patients with thyrotoxic heart disease than those of normal subjects （t = 6.23, P 〈 0.01 ）. valva mitralis prised-wave rate of E/A was lower than subjects （ t = 6.39,P 〈 0.05 ）. LVMI correlated negatively with E/A （ r = - 0.79,P 〈 0.01 ）. Conclusion Thyrotoxic heart disease was earlier diagnosed and its left ventricular function was assesssed by LVMI and E/A.