摘要
目的探讨阿托伐他汀及阿司匹林对冠心病患者C-反应蛋白的影响。方法观察109例冠心病患者的C-反应蛋白在用药前后的变化。其中阿托伐他汀组37例,阿司匹林组29例,阿托伐他汀和阿司匹林联用组43例。结果3组患者用药前后C-反应蛋白的改变差异均有统计学意义(P<0.05),而阿托伐他汀及阿司匹林联用组用药后C-反应蛋白的浓度与另两组用药后C-反应蛋白的浓度比较差异亦有统计学意义(P<0.01)。结论阿托伐他汀和阿司匹林联用对C-反应蛋白的降低优于单一的阿托伐他汀或阿司匹林。
Objective To study the effects of atorvastatin and aspirin on C-reactive protein（CRP） in patients with coronary artery disease. Methods The changes of CRP concentrations before and after the treatment in 109 patients with coronary .artery disease were investigated. Among these patients ,37 were in atrovastatin group,29 in aspirin group and 43 in atrovastatin and aspirin group. Results The CRP concentrations in the three groups after the treatment were significantly lower than those before the treatment, In addition ,the CRP in atrovastatin and aspirin group were significantly lower＇than those in the other two groups after the treatment（P〈0.01）. Conclusion The reduction effects of atorvastatin and aspirin on CRP concentrations are superior to those of single atorvastatin or aspirin.
出处
《内科》
2008年第1期10-11,共2页
Internal Medicine
