不同剂量血脂康治疗原发性高脂血症81例

CLINICAL OBSERVATION ON DIFFERENT DOSE EFFICACY OF XUEZHIKANG IN TREATMENT OF PRIMARY HYPERLIPIDEMIA

观察８１例原发性高脂血症患者用不同剂量血脂康的治疗效果，随机分为２组，Ａ组（３９例）服血脂康２粒／次，早晚各１次（１．２ｇ／ｄ），Ｂ组（４２例）服血脂康３粒／ｄ，每晚１次（０．９ｇ／ｄ），疗程均为８周。结果显示服血脂康后两组各血脂水平与治疗前比较，ＴＣ、ＴＧ、ＬＤＬＣ、（ＴＣ－ＨＤＬＣ）／ＨＤＬＣ均明显下降（Ｐ＜０．０１～＜０．００１），ＨＤＬＣ明显上升（Ｐ＜０．０１）；不同剂量血脂康降ＴＣ、ＴＧ、ＬＤＬＣ、（ＴＣ－ＨＤＬＣ）／ＨＤＬＣ，升ＨＤＬＣ的幅度无明显差异（Ｐ均＞０．０５）。提示每晚服３粒血脂康可获得较好的降脂疗效。

The study was conducted on 81 patients with primary hyperlipidemia.They were randomly divided to receive 4 capsules daily (1.2 g/d)(n=39) or 3 capsules daily (0.9 g/d)(n=42)for 8 weeks.At the end of the study the serum TC,TG,LDL C and (TC-HDL C)/HDL C were all decreased in both groups in comparison with baseline values and the serum HDL C was all increased in both groups and no significant difference were observed.Therefore,the effective dose of Xuezhikang capsule should be 3 capsule daily.