用正交试验探讨大黄煎煮条件对大黄酚含量的影响

Study on the Effect of Decocting Condition of Rhubarb on Chrysophanol Content with Orthoginal Design

采用正交试验，以漫膏得率和大黄酸含量为考察指标，对大黄药材的煎煮条件进行优选，结果表明以8倍于生药重量的水浸泡30分钟，煎煮10分钟为佳；同时进行了方法学研究，结果表明方法可行、工艺稳定、重现性好。

Taking obtaining rate of extract and content of Chrysophanol as parameters,the decocting condition of rhubarb wasstudied with orthoginal design.The results showed that the best outcome would be obtained when the crude drug was immersed ineight-fold water in weight for 30 minutes and decocted for 10 minutes.Study of methodology was carried out as well.We considerthat this method is feasible,stable and has good repeatability.