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动脉内溶栓治疗36例急性缺血性脑梗死临床分析 被引量:3

Intra-artery thrombolysis therapy for acute ischemic cerebral infarction:clinical analysis of 36 cases
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摘要 目的探讨急性脑梗死行局部动脉内溶栓治疗的临床疗效及安全性。方法选择36例起病至溶栓时间在4~24h之内的急性缺血性脑梗死患者,经股动脉插管行全脑血管造影术发现闭塞血管后,用注射泵缓慢注射尿激酶行局部溶栓治疗,并通过导引导管造影,了解闭塞再通情况。结果36例中治愈16例,显效13例,有效6例,无效1例,显效率80.5%,总有效率97.2%。结论动脉插管接触性溶栓治疗急性脑梗死疗效确切,是治疗脑梗死有效的治疗手段。 Objective To evaluate the clinical effects of intra-artery thrombolysis therapy for acute ischemic cerebral infarction (AICI). Methods Thirty-six patients of AICI in 4--24 h were treated with intra-arterial thrombolysis by urokinase within 1 million IU. Results Sixteen patients received complete recanalization. Significant effective was found in 13 patients, while effective in 6, resulting the total effective rate of 97.2%. Conclusion Intra-artery thrombolysis therapy for AICI is a safe and effective therapeutic method of AICI.
出处 《中国介入影像与治疗学》 CSCD 2008年第2期109-111,共3页 Chinese Journal of Interventional Imaging and Therapy
关键词 急性脑梗死 动脉插管溶栓 尿激酶 Cerebral infarction Intra-artery thrombolysisacute Urokinase
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  • 1[3]Wiss RJS.Serial observations on the pathophysiologv of acute stroke:The transition from ischemia to infarction as reflected in regional oxgen extraction.Brain,1983,106:197-222.
  • 2[6]Jahan K,Dduckwiler Uuckwiler GR,Kidwell CS,et al.Intraarterial thrombolysis for treatment of acute stroke:experience in 26 patients with long-term follow-up.AJNR Am J Neuroradiol,1999,20(7):1291-1299.
  • 3[8]Wardlaw JM,Warlow CP.Thrombolysis in acute ischemic stroke:Doesitwork? Stroke,1992,23(12):1826-1939.

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