代谢综合征其它组分与高血压的关系

The relationship between elements of metabolic syndrome and hypertention

2005年4月,国际糖尿病联盟统一使用"代谢综合征"概括相关临床表型,其主要成分包括中心性肥胖、血脂代谢异常、血糖升高和(或)胰岛素抵抗及高血压。其中,高血压的发生原因复杂,代谢综合征中的其它组分包括中心性肥胖、血脂代谢异常、胰岛素抵抗等最终都能引起高血压并影响其发展过程,其中,中心性肥胖的影响最为关键。代谢综合征是2型糖尿病和心血管疾病的高危因素,早期诊断和早期干预,有助于2型糖尿病和心血管疾病的防治。本文综述代谢综合征其它组分与高血压的关系。

Metabolic syndrome（MS） is characterized by the cluster of obesity, dyslipidemia, insulin resistance and hypertension. The pathogenesis of hypertension is complex and multifactorial and other elements of MS, including obesity, dyslipdemia and insulin resistance probably are involved in the pathogenesis of hypertension and affect its progression. Of these elements, obesity may play the most important and pivotal role in leading to hypertension in MS. MS is associated with increased risk of type 2 diabetes mellitus and cardiovascular disease. In this article, we reviewed the relationship between other elements of MS and hypertention.