输液宝加纳洛酮治疗重度一氧化碳中毒28例疗效分析

The Efficacy Analysis of Disposable Infusion Oxygen Storage Tank Combined with Naloxone in the Treatment of 28 Serious Carbon Monoxide Poisoning Patients

目的探讨纳洛酮加输液宝治疗急性CO中毒的疗效和安全性。方法将46例急性重度CO中毒患者随机分为两组,对照组18例鼻饲吸氧加常规治疗,治疗组28例在对照组治疗基础上加输液宝和纳洛酮。结果对照组18例重度中毒患者12例治愈,总有效率66.7%,其中2例死亡,3例中途放弃,1例迟发性脑病;治疗组28例重度中毒患者27例治愈,死亡1例,总有效率96.4%。结论输液宝加纳洛酮治疗急性CO中毒具有恢复时间快、治愈率高的特点,降低了病死率和后遗症的发生率。

Objective To discuss the efficacy and safety of applying disposable infusion oxygen storage tank and naloxone to cure acute carbon monoxide（CO） poisoning. Methods To divide the 46 acute serious CO poisoning patients into two groups at random. The control group with 18 patients got oxygen through nasal cannulae. And conventional treatment,the active group with 28 patients applying disposable infusion oxygen storage tank and naloxone besides the conventional treatment. Results 12 patients were cured in the control group, the total effective rote was 66.7%, and two patients died, three withdrew midway, and one suffered delayed encephalopathy. 27 serious poisoning patients were cured in the active group, one died, the total effective rate was 96.4%. Conclusion The recovery time of the acute CO poisoning patients applying disposable infusion oxygen storage tank and naioxone was short, and the recovery rate was high, this therapy could reduce the mortality and the sequela occurrence.