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炎症因子基因多态性及其功能蛋白与阿尔茨海默病的关系 被引量:7

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摘要 阿尔茨海默病是一种慢性中枢神经系统的变性疾病。最近大量的研究发现,炎症反应也是阿尔茨海默病发病的重要机制之一。目前的研究发现,炎症因子白介素-1α、白介素-1β、肿瘤坏死因子α、α2巨球蛋白和α1-抗糜蛋白酶的基因多态性及其表达的功能蛋白增加了阿尔茨海默病的发病风险。因此对炎症反应的研究将为阿尔茨海默病的预防和治疗提供新的方法。
作者 王钰 张本恕
出处 《国外医学(老年医学分册)》 2008年第2期68-71,共4页 Foreign Medical Sciences(Geriatrics)
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参考文献24

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二级参考文献38

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