摘要
目的:观察脑得生处方不同工艺下对颈动脉血栓形成的抑制作用。方法:用动-静脉旁路血栓形成和体外凝血时间等方法。结果:连续灌胃脑得生各处方7d后,处方1在4.28,2.14g(生药).kg-1,处方3在4.28g(生药).kg-1,均能明显抑制实验性动-静脉环路中血栓形成,血栓湿重分别降低26.1%,29.3%,22.3%;但是对小鼠体外凝血时间无明显影响。结论:活血化淤作用依次为处方1>处方3>处方2。
OBJECTIVE To study the effect of the Naodesheng from different extract processing on the thrombosis and coagulation of rats and mices. METHODS Using the method of arteriovenous bypass thrombosis and the clotting-time of mice. RESULTS After the rats were treated for 7 days, the first prescription was effective to inhibit the thrombosis of rats, inhibition rates were 2. 7%, 26. 1%,29. 3 %, the first prescription of Naodesheng （2. 14 g· kg^-1 , ig） and the third prescription （4. 28 g· kg^-1 ,ig） had effect on the thrombosis of rats,inhlbition rate was 22.3%. There was no significant difference in the clotting time of mices. CONCLUSION The order of activating blood circulation, is prescription 1〉3〉2.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2008年第4期281-283,共3页
Chinese Journal of Hospital Pharmacy
关键词
脑得生
抗血栓
药理
Naodesheng capsules
thrombosis
pharmacology
