阿托伐他汀对高胆固醇血症的疗效观察

Effect of atorvastatin on hypercholesterolemia

目的:观察阿托伐他汀钙片治疗高胆固醇血症疗效,并探讨其机制。方法:对120例高胆固醇血症患者采取回顾性分析的方法,比较治疗前后血脂水平的变化。结果:经治疗,总有效率达74.2%,所有患者的血脂水平与治疗前比较,差异有显著性(P<0.05)。结论:阿托伐他汀钙片治疗高胆固醇血症效果满意,不良反应轻,可广泛应用于临床。

OBJECTIVE To observe the effect of atorvastatin on the treatment of hypercholesterolemia and its mechanism. METHODS 120 cases of hospital patients with hypercholesterolemia were collect for the retrospective analysis, the changes in serum lipid levels before and after treatment were compared. RESULTS After treatment, the total efficiency was 74. 2%, the difference of the serum lipid levels in all patients was significant（P〈0. 05） compared with the levels before the treatment. CONCLUSION The treatment of hypercholesterolemia with atorrastation is safe,which can be widely used in clinical practice.