氧化偶联反应制备β-胡萝卜素

Improved Coupled-oxidation for Preparation of β-Carotene

维生素A与三苯膦在硫酸作用下反应得到的鏻盐,于水和氯仿的两相体系中用次氯酸钠进行两分子氧化偶合,得到β-胡萝卜素,收率约51%。

β-Carotene was prepared from retinal with triphenylphosphine in the presence of sulfuric acid to obtain the corresponding phosphonium salt, followed by the coupled-oxidation with sodium hypochlorite in two-phase system （chloroform and water） with a yield of about 51%.