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冠心病患者不同糖代谢状况与冠状动脉病变的关系

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摘要 目的探讨冠心病患者不同糖代谢状况下的冠状动脉病变特征。方法选择住院期间经冠状动脉造影确诊的冠心病患者,均在确诊后进行75g葡萄糖耐量实验(OGTT试验)测定0h及糖负荷后2h血糖,根据1999年世界卫生组织糖尿病诊断标准,分为3组:(1)糖耐量正常(NGT)组68例,(2)糖耐量异常(IGT)组76例,(3)2型糖尿病(T2DM)组62例。通过冠状动脉造影评价,3组的冠状动脉病变特征,分析其与血糖的关系。结果(1)T2DM组和IGT组与NGT组相比,冠状动脉多支病变的发生率,末梢病变及弥漫性病变所占比例以及冠状动脉狭窄指数积分明显高于NGT组。(2)T2DM组与IGT组相比,冠状动脉病变特征相似。(3)本组冠心病患者,T2DM组及IGT组患病率分别为30.1%、36、9%。结论糖耐量异常和糖尿病者冠状动脉病变较严重,表现为多支、弥漫和末梢血管病变。在冠心病患者中T2DM及IGT的患病率高。
出处 《中国医师杂志》 CAS 2008年第2期239-241,共3页 Journal of Chinese Physician
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