醒脑静注射液治疗急性脑出血疗效Meta分析

Meta-analysis of Xingnaojing Injection on Treatment of Acute Cerebral Haemorrhage

目的:利用Meta分析方法对醒脑静注射液治疗急性脑出血的临床试验进行分析,评价其治疗效果。方法:检索1994～2006年国内发表的醒脑静注射液治疗急性脑出血临床试验的相关文献,应用Meta分析对7篇研究进行同质性检验和合并效应量的估计。结果:①同质性检验:x^2=2.3684,自由度7,P>0.05。②合并效应量的估计:OR合并95%可信区间为2.830 6-4.267 8。OR合并的检验:x^2=36.829 0,P<0.005。结论:醒脑静注射液治疗急性脑出血安全有效。

Objective： To observe the therapeutic effect of Xingnaojing Injection on patients with acute cerebral haemorrhage. Method： The elinieal trials of Xingnaojing Injection on the treatment of acute eerebral haemorrhage were eolleeted from 1994 -2006, the meta analysis of 7 artieles were used to make an estimation of homogeneity test and overall effect, Result： （1）Homogeneity test ：X^2 = 2.3684, df was 7, P 〉 0.05. （2） Estimation of merging effect value ： OR merging 95 % confidence interval was ： 2. 830 6 - 4. 267 8. OR merging test ： X^2 =36.829 0, P 〈0.005. Conclusion： Xingnaojing Injection in treatment of acute cerebral haemorrhage is safe and effect.