摘要
1名61岁男性胃癌晚期患者,术后化疗给予多西他赛40mg/m2静脉滴注,亚叶酸钙120mg/m2静脉滴注,氟尿嘧啶800mg/m224h中心静脉持续滴注,配合羟基喜树碱15mg腹灌和热疗2个周期。用药结束后第5天患者出现双下肢进行性可凹性水肿。给予甲泼尼龙、呋塞米治疗4d后,水肿消退。
A 61 year-old man with advanced gastric carcinoma received chemotherapy with IV docetaxel 40 mg/m^2 , IV calcium folinate 120 mg/m^2, and fluorouracil 800 mg/m^2 via a central vein for 24 hours, in combination with two cycles of intraperitoneal hydroxycamptothecin 15 mg and thermotherapy after the surgery. On day 5 after the chemotherapy, he developed progressive pitting oedema of the lower extremities. After 4 days of treatment with methylprednisolone and furosemide, his oedema resolved.
出处
《药物不良反应杂志》
2008年第1期60-61,共2页
Adverse Drug Reactions Journal
关键词
多西他赛
下肢水肿
docetaxel
oedema of lower extrmities
