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孟鲁司特钠咀嚼片与膝关节痛相关 被引量:13

Knee pain associated with montelukast sodium chewable tablets
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摘要 1名5岁女童因支气管肺炎咳嗽,给予布地奈德雾化混悬液2ml吸入,2次/d,酮替芬0.5mg,2次/d,丙卡特罗12.5μg,2次/d,孟鲁司特钠咀嚼片5mg,1次/d。次日出现左膝关节疼痛,停用孟鲁司特钠咀嚼片,其他药品继续使用,2天后疼痛缓解。2周后再次使用布地奈德气雾剂200μg,2次/d,孟鲁司特咀嚼片5mg,1次/d。3d后,又出现膝关节疼痛,伴腿部肌肉僵硬。再次停用孟鲁司特,7d后膝关节疼痛缓解。又过2d,其症状消退。 A 5-year-old girl with bronchial pneumonia received budesonide nebulising suspension 2 ml twice daily, oral ketotifen 0.5 mg and procaterol 12.5 μg twice daily, montelukast sodium chewable tablets 5 mg once daily for treating cough. The next day, she developed left knee pain. Montelukast sodium chewable tablets were withdrawn, and other drugs were continued. Knee pain resolved after two days. Two weeks later, treatment with budesonide aerosol 200 μg twice daily and montelukast sodium chewable tablets 5 mg once daily was re-administered. Knee pain with muscle stiffness of the legs occurred again 3 days later. Montelukast was discontinued again. Seven days later, knee pain was relieved. Another 2 days later, his symptoms resolved.
出处 《药物不良反应杂志》 2008年第1期62-62,共1页 Adverse Drug Reactions Journal
关键词 孟鲁司特 膝关节痛 montelukast knee pain
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