慈菇银屑胶囊治疗银屑病出现血小板和白细胞减少

Thrombopenia and leucopenia occurring with Ciguyinxie capsules for treating psoriasis

一名48岁男性银屑病患者,晨服慈菇银屑胶囊1号4粒,晚服慈菇银屑胶囊3号4粒,以及慈菇康肤宝贴剂(主要成分为山慈菇)治疗1年。因病情加重入院,查WBC3.2×109/L,PLT50×109/L,HB90g/L。次日复查血常规,WBC、PLT、HB分别降至2.6×109/L、19×109/L、82g/L。停用慈菇银屑胶囊及慈菇康肤宝贴剂,给予重组人粒细胞刺激因子、地塞米松、血小板悬液等对症支持治疗。3天后复查血常规各项指标均恢复正常。

A 48 year-old man with psoriasis had been treated for one year with Ciguyinxie capsules No. 1 （ four capsules daily in the morning）, Ciguyinxie capsules No. 3 （four capsules daily at night） , and Cigukangfubao patches（ The main ingredient of the three preparations is pseudobulb of appendiculate cremastra ）. The patient was hospitalized with aggravated psoriasis. Blood routine test revealed a WBC count of 3.2 × 10^9/L, a PLT count of 50 × 10^9/L, and a HB level of 90 g/L. On the second hospital day, a reexamination showed that his WBC count, PLT count, and HB level were decreased to 2.6 ×10^9/L, 19 ×10^9/L, and 82 g/L, respectively. Ciguyinxie capsules and Cigukangfubao patches were discontinued and the patient received recombinant human granulocyte stimulating factor, dexamethasone and platelet suspension. Three days later, his blood routine values returned to normal limits.