大肠类癌术后复发转移的危险因素分析

Analysis of risk factors for recurrence and metastases after resection of carcinoid of large intestine

目的探讨大肠类癌术后复发转移的危险因素,为预测和预防大肠类癌术后复发提供依据。方法回顾性分析我院2000年1月～2005年10月收治的大肠类癌19例的临床资料。结果肿瘤直径≥2.5cm者12例,术后复发转移8例;肿瘤直径<2.5cm的7例仅有2例复发转移。肿瘤已浸润至肌层、浆膜者14例,复发转移9例;浸润深度不超过肌层的5例中仅有1例复发。淋巴结转移阳性的5例术后全部复发转移,而淋巴结转移阴性者只有5例复发转移。结论对于大肠类癌手术是有效的治疗手段。应根据肿瘤大小、浸润深度及淋巴结转移与否来选择手术方式。

Objective To explore the risk factors of recurrence and metastases of carcinoid of large intestine after operation and provide evidences for predicting and preventing recurrence after resection. Methods The clinical and pathological data of 19 patients with carcinoid of large intestine who were operated on in our hospital from Jan. 2000 to Oct. 2005 were analyzed restrospetively in this study. Results In 12 cases with the diameter of tumor ≥2. 5 cm,postoperative recurrence and metastases occurred in 8 cases. In 7 cases with the diameter 〈2. 5 cm, the recurrence and metastases occurred in 2 cases. In 14 cases with invasion of tumor into muscle layer and serosa, the recurrence and metastases occurred in 9 cases. In 5 cases with invasion of tumor not into mucosa,only one case had recurrence and metastases. In 5 cases with lymph node metastasis, recurrence and metastases occurred in all cases. In 14 patients without lymph node metastasis,only 5 cases had recurrence and metastases. Conclusion Surgical removal is an effective treatment. According to diameter of tumor, depth of invasion and lymph node metastais,surgical procedures were selected.