长春地区孕产妇和肿瘤病人血清弓形虫抗体IgG的检测

Detection of antibody IgG against Toxoplasma gondii from pregnant/parturient women and cancer patients in Changchun region

目的检测长春地区孕产妇和肿瘤病人弓形虫感染抗体IgG。方法采用酶联免疫吸附试验对47例孕产妇和267例恶性肿瘤病人血清标本进行弓形虫抗体检测。结果长春地区孕产妇和肿瘤病人血清弓形虫抗体IgG阳性率分别为10.64%和23.97%,显著高于健康人群阳性率6.08%(P<0.05);鼻咽癌和直肠癌患者弓形虫抗体IgG阳性率高于其他类型肿瘤病人(P<0.01)。结论孕产妇和肿瘤病人为弓形虫易感人群,应作常规性弓形虫抗体检测。

Objective To determine Toxoplasma gondii antibodies in pregnant/parturient women and Methods Fourty seven pregnant/parturient women and 267 cancer patients were studied using ELISA cancer patients. Results Higher positivity rates of T. gondii IgG were detected in pregnant/parturient women and cancer patients than the control. The positivity rates of T. gondii IgG in nasopharyngeal carcinoma, rectal cancer groups were significantly higher than the other cancer groups, demonstrating that the mucosal defences have important roles in T. gondii infection based on special anatomical locations of cancer. Conclusion Toxoplasma gondii antibodies should be routinely detected in some special populations, such as pregnant/parturient women and cancer patients.