镇心痛对冠心病心绞病心功能及血液流变学的影响

Influence of Zhenxintong Oral Liquor on Cardiac Function and Hemorheology in Petients with Angina Pectoris of Coronary Heart Disease

目的：探讨镇心痛对冠心病心绞痛患者心功能及血液流变学的影响。方法：将64树冠心病心绞痛患者应用镇心痛口服液治疗30天，用电脑超声仪观察治疗前后心功能射血分数（EF）、心脏每分钟射血量（CO）、心脏指数（CI）、左室舒张末期容积（EDV）、左室收缩末期容积（ESV）。血液流变学观察全血比低、高切粘度及血浆比粘度、红细胞压积双纤维蛋白原。结果：治疗后较治疗前EF有显著升高（P＜0．01），CO、CI升高，ESV降低（p＜0．05）。全血比高切粘度、血浆比粘度、纤维蛋白原有显著下降（P＜0．01），全血比低切粘度、红细胞压积明显下降（P＜0．05）。结论：镇心病对冠心痛心绞痛患者心功能及血液流变学具有明显疗效。

The influence of Zhenxintong on cardiac function and hemorheology were observed in 64 cases of angina pectoris of CHD,who were treated with this medicine for 30 days. The Parameters of heart function of ejection fraction (EF),cardiac output (CO), cardiac index (CI), end diastolic volume (EDV)and end systolic volum(ESV) were measured with computerized ultrasonic imaging appartus before and after treatmentThe results showed that EF markedly increased (P<0.01),CO and CI increased and ESV decreased (P<0.05) after treatment. Oborvation on hemorheology showed that the whole blood high viscosity,plasma viscosity and fibrinogen had been markedly reduced (p<0. 01), the whole blood low viscosityand packed cell volume had been reduced (P<0. 05). Above results revealed that Zhenxintong has obvious effect on cardiac function and hemorheology of angina pectoris of CHD.