期刊文献+

感染后功能性胃肠病及其发病机制 被引量:3

Postinfectious Functional Gastrointestinal Disorders and its Pathogenic Mechanism
下载PDF
导出
摘要 功能性胃肠病(FGIDs)是一类常见胃肠道疾病,其发病和特定症候群与多种因素相关。胃肠道感染和黏膜炎症背景作为FGIDs发病的诱因近年来备受关注。学者们将那些感染后发生的FGIDs称为感染后FGIDs(PI-FGIDs)。本文就感染与FGIDs的关系以及PI-FGIDs发病机制中的动力异常、黏膜免疫改变、肠神经系统改变等内容作一介绍。 Functional gastrointestinal disorders (FGIDs) are commonly seen diseases of gastrointestinal tract. The pathogenic mechanism and symptoms of FGIDs are related with many factors. Recent studies have focused on gastrointestinal infection and mucosal inflammation as the causative factor of FGIDs, and FGIDs following infection are called postinfectious FGIDs (PI-FGIDs). This article reviewed the recent progress of the relationship between infection and FGIDs and the factors involved in the pathogenesis of PI-FGIDs, such as dysmotility, and changes of mucosal immunity and enteric nervous system.
出处 《胃肠病学》 2008年第2期72-75,共4页 Chinese Journal of Gastroenterology
关键词 感染 炎症 免疫 黏膜 功能性胃肠病 Infection Inflammation Immunity, Mucosal Functional Gastrointestinal Disorders
  • 相关文献

参考文献38

  • 1Drossman DA. The functional gastrointestinal disorders and the Rome Ⅲ process. Gastroenterology, 2006, 130 (5): 1377-1390.
  • 2Gwee KA, Leong YL, Graham C, et al. The role of psychological and biological factors in postinfective gut dysfunction. Gut, 1999, 44 (3): 400-406.
  • 3Parry SD, Stansfield R, Jelley D, et al. Does bacterial gastroenteritis predispose people to functional gastrointestinal disorders? A prospective, communitybased, case-control study. Am J Gastroenterol, 2003, 98 (9): 1970-1975.
  • 4McKeown ES, Parry SD, Stansfield R, et al. Postinfectious irritable bowel syndrome may occur after non-gastrointestinal and intestinal infection. Neurogastroenterol Motil, 2006, 18 (9): 839-843.
  • 5Soyturk M, Akpinar H, Gurler O, et al. Irritable bowel syndrome in persons who acquired trichinellosis. Am J Gastroenterol, 2007, 102 (5): 1064-1069.
  • 6Dobronte Z, Lakner L, Sarang K. Postinfectious irritable bowel syndrome. Orv Hetil, 2006, 147 (43): 2077-2080.
  • 7Marshall JK, Thabane M, Borgaonkar MR, et al. Postinfectious irritable bowel syndrome after a food-borne outbreak of acute gastroenteritis attributed to a viral pathogen. Clin Gastroenterol Hepatol, 2007, 5 (4): 457-460.
  • 8Spiller RC. Role of infection in irritable bowel syndrome. J Gastroenterol, 2007, 42 Suppl 17: 41-47.
  • 9Kindt S, Caenepeel P, Arts J, et al. Characteristic and determinants of long-term outcome in acute onset functional dyspepsia patients. Gastroenterology, 2006, 130 (4 Suppl 2): A134.
  • 10de Freitas D, Urbano M, Goulao MH, et al. The effect of Helicobacter pylori infection on apoptosis and cell proliferation in gastric epithelium. Hepatogastroenterology, 2004, 51 (57): 876-882.

二级参考文献58

  • 1李延青,张海燕,左秀丽,袁海鹏,卢雪峰,李君曼.肠易激综合征患者肠黏膜Th1/Th2漂移的研究[J].中华消化杂志,2004,24(12):728-731. 被引量:74
  • 2金冠球,肖正达,朱剑耀,姚季生,谢宇野,张思义,李永平,吕礁.92例非溃疡性消化不良患者的胃电图、胃动素、胃泌素及粘膜肥大细胞的观察[J].中华消化杂志,1995,15(1):54-55. 被引量:37
  • 3桂先勇,潘国宗,柯美云,陈国钧.胃肠肽在应激所致结肠动力紊乱中的作用[J].中华医学杂志,1997,77(1):31-34. 被引量:38
  • 4杨云生,周殿元,张万岱,张振书,宋于刚.肠易激综合征回盲部肥大细胞的研究[J].中华内科杂志,1997,36(4):231-233. 被引量:47
  • 5Simren M, Tack J. Functional dyspepsia: evaluation and treatment.Gastroenterol Clin North Am, 2003, 32: 577-599.
  • 6Barbara G, De Giorgio R, Stanghellini V, et al. A role for inflammation in irritable bowel syndrome? Gut, 2002, 51 suppll:i41-44.
  • 7Tack J, Demedts I, Dehondt G, et al. Clinical and pathophysiological characteristics of acute-onset functional dyspepsia.Gastroenterology, 2002, 122: 1738-1747.
  • 8Li XB, Liu WZ, Ge ZZ, et al. Analysis of clinical characteristics of dyspeptic symptoms in Shanghai patients. Chin J Dig Dis, 2005,6 :62-67.
  • 9Talley NJ, Janssens J, Lauritsen K, et al. Eradication of Helicobacter pylori in functional dyspepsia: randomised double blind placebo controlled trial with 12 months' follow up. The Optimal Regimen Cures Helicobacter Induced Dyspepsia (ORCHID) Study Group. BMJ, 1999, 318: 833-837.
  • 10Chey WD, Moayyedi P. Review article: uninvestigated dyspepsia and non-ulcer dyspepsia-the use of endoscopy and the roles of Helicobacter pylori eradication and antisecretory therapy. Aliment Pharmacol Ther, 2004, 19 (Suppl 1) : 1-8.

共引文献144

同被引文献38

引证文献3

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部