金沉积复合镍铬合金烤瓷的镍离子析出量的实验研究

Quantity of released nickel ion from Ni-Cr alloy of compound galvano-ceramic bridge

目的通过测试浸泡在人工唾液中的金沉积片复合镍铬合金片烤瓷试件的镍离子析出量，探究金沉积基底冠熔结镍铬桥体烤瓷桥是否能减少镍离子析出，降低生物安全风险。方法将镍铬合金片与金沉积片粘接，表面烤瓷，瓷层厚度分别为0．3mm（A组）、0．5mm（B组）、1．0mm（C组）和0．3mm（D组），每组6个试件。对照组为镍铬合金片。A、B、C组和对照组浸泡在37℃酸性人工唾液中；D组浸泡在37℃酸性高氟人工唾液中。浸泡120h后，测定浸泡液的镍离子浓度。独立样本t检验比较A—D组浸泡液镍离子浓度与对照组的差异。结果A、B、C、D组的镍离子浓度均小于0．005mg／L；与对照组[（0．65±0．45）mg／L]相比，差异均有统计学意义（P〈0．05）。结论金沉积基底冠熔结镍铬桥体烤瓷桥可减少镍离子析出，降低生物安全风险。

Objective To evaluate the biological safety of compound galvano-ceramic bridge by measuring the consistency of released nickel ion of the galvano-form slices cohered with Ni-Cr alloy slice specimens which were immersed in artificial saliva. Methods Specimens were divided into five groups with four tests and one control. Test specimens were made into the structure like rectangle sandwich that one side of Ni-Cr alloy was cohered to the center surface of galvano golden base of 0. 2 mm and another side was fused porcelain with the thickness of 0. 3 mm （ group A）, 0. 5 mm （ group B）, 1.0 mm （ group C ）, and 0. 3 mm （group D）. And the Ni-Cr alloys were totally embedded in galvano golden base and firing porcelain. Naked Ni-Cr alloy was taken as control. Group D was immersed into acid artificial saliva （AS） with high fluoride, while others were in acid AS at 37 ℃ for 120 h. Then the consistency of released nickel ion in the solution was measured with inductively coupled plasma-atomic emission spectrometry （ ICP-AES）. Results Nickel ions detected in the artificial saliva for the groups A, B, C, and D in acid AS with or without high fluoride were all under 0. 005 mg/L Significant differences were found between each test group and the control [ （0. 65 ± 0. 45） mg/L]. Conclusions Galvano-ceramic bridge, Ni-Cr alloy bridge with fused porcelain and golden base, shows biological safety responsible for the consistency of released nickel ion.