影像学检查对早期股骨头缺血坏死诊断意义的实验研究

Early-Stage Avascular Necrosis of Femoral Head(ANFH): Experimental Study of Diagnosal Significance by Imaging Examinations.

目的：通过动物实验研究，观察比较Ｘ线、ＥＣＴ、ＭＲＩ对于早期股骨头缺血坏死的诊断意义，提高早期股骨头缺血坏死的早期诊断率。材料方法：以５组（每组４只）共２０只成年犬，手术结扎一侧股骨头所有滋养动脉，观察术后３天、７天、１４天、３０天及４５天的影像学改变。结果：Ｘ线仅在术后４５天组中有２只犬有片状低密度改变。ＥＣＴ仅提示股骨头血液灌注不良。ＭＲＩ在术后７天就发现有点状低信号改变。结论：ＭＲＩ、ＥＣＴ均比普通Ｘ线敏感，而ＭＲＩ是诸方法中最敏感的。

PURPOSE:To know and compare the diagnosal significance for early-stage ANFH by X-rays, ECT and MRI examination, and to improve the rate of diagnosis for early-stage ANFH; MATRIAL AND METHOD:20 adult dogs divided into 5 group(4 each group) were used. All the nutrient arteries of either side of femoral head were ligated by surgery. Then we observed the imaging changes after 3 days, 7 days, 14 days, 30 days and 45 days;RESULT:Low-density patchy shadow could be seen in X-rays films in only 2 dogs after 45 days. ECT examination only indicated the malinfusion of blood of invoved femoral head, while 7 days postoperation spotted low signal could be found in MRI;CONCLUSION:MRI and ECT are more sensitive than X-ray film in detecting ANFH, and MRI is the most sensitive way of the three.