抑郁性神经症病人的痛觉阈值测定

A study of pain perception threshold in patients with depressive disorders

比较３０例抑郁性神经症、抑郁症患者与正常对照组的躯体感觉阈（ＳＰＴ）、痛觉阈（ＰＰＴ）及相对痛觉阈（ＲＰＰＴ）。发现抑郁性神经症和抑郁症患者ＳＰＴ和ＰＰＴ均明显高于正常对照组；病程与痛觉阈值无显著相关性；抑郁性神经症与重症抑郁患者之间的ＳＰＴ、ＰＰＴ及ＲＰＰＴ值无显著差异。提示内源性疼痛调节系统与抑郁症状和／或神经症的病理基础可能存在生物学联系。

Objective:To compare pain perception threshold between patients with depressive neurosis and patients with depression. Method:Somatosensory perception threshold (SPT),pain perception threshold (PPT)and relative pain perception threshold (RPPT) were investigated in 30 patients with depressive neurosis,30 patients with depression and 30 normal control subjects. Results:The SPT and PPT of patients with depressive neurosis and depression were significantly higher than those of normal control subjects.There was no significant correlation between duration of illness and PPT. No significant differences in SPT,PPT and RPPT were found between patients with depressive neurosis and patients with depression. Discussion:Endogenous pain modulating system may be related to depressive symptoms or the biopathological mechanism of neurosis.