光固化型玻璃离子水门汀的体外细胞毒性

In vitro cytotoxicity of light-cured glass ionomer cements

目的：比较８种光固化型玻璃离子水门汀的体外细胞毒性。方法：采用牙髓细胞体外培养技术和四唑盐（ＭＴＴ）显色分光光度法。结果：除１种含金属离子的加强型玻璃离子水门汀外，其余７种玻璃离子水门汀呈较弱的体外细胞毒性。８种玻璃离子水门汀的体外细胞毒性从小到大依次为：Ｄｙｒａｃｔ，ＦｕｊｉⅡＬＣ，Ｇｅｒｉｓｔｏｒｅ，ＣｈｅｍＦｉｌⅡ，ＰｈｏｔｏＦｉｌ，Ｖｉｔｒｅｍｅｒ，Ｒｅｓｉｎｏｍｅｒ，Ｈｉ－Ｄｅｎｓｅ．结论：光固化型玻璃离子水门汀的体外细胞毒性较弱。

Aim:To compare in vitro cytotoxicity of eight light-cured glass ionomer cements (GICs). Methods: Using in vitro pulp cell culture technique and MTT staining and spectrophotometric assay. Results: The toxic effect of GICs on in vitro pulp cells was relative lower in spite of Hi-Dense, one kind of silver ions reinforced cement. The rank of cytotoxicity (from low to high) was: Dyract, Fuji Ⅱ LC, Geristore, Chem FilⅡ, Photo Fil, Vitremer, Resinomer, Hi-Dense. Conclusions: In vitro cytotoxicity of light-cured GICs is low, but metal ions reinforced GIC has a greater cytotoxicity.