青年人胃癌

Gastric carcinoma in the young people

作者分析了１９７６年～１９９１年间６７５例胃癌病例的临床病理情况及随访结果，将其中年龄≤３５岁的青年组胃癌５１例与年龄＞３５岁的６２４例中老年组相比较。分析结果：（１）青年组胃癌发病男、女之比为１∶１．２，比值随年龄而增加，至５０～５９岁达高峰为２．８∶１。（２）青年组胃癌组织学分化较差者占８８．２％，明显高于中老年组（Ｐ＜０．０１）。（３）青年组胃癌分期多数偏晚，Ⅲ、Ⅳ期占７２．５％（Ｐ＞０．１）。作者认为：青年组与中老年组在手术切除率及术后生存率方面差异均无显著意义，大多数青年患者诊断较晚，争取早期发现是改善预后的主要措施。

We studied the characteristics of the incidence, and prognosis of the gastric carcinoma in young people. The clinicopathological findings and follow up data of the gastric carcinoma patients treated from 1976 to 1991 were compared in 624 olderly patients. The male to female ratio was 1: 1 2 in young patients and it increased with age up to a peak: in the 50～59 year old group(2 8∶1). An increase of poorly differentiated tumors was found significantly in the young people (88 2%) compared with the olderly ( P <0 01). A slight preponderance of diseases in stage Ⅲ and Ⅳ was found in the young people (72 5%, P >0 1). There was no significant difference of resectability and postoperative actuarial survival between the two groups. Most young patients were diagnosed in the late stage. Early detection of the carcinima in the young patients plays a significant role in improving their treatment results.