乳腺癌综合治疗的远期疗效(附702例报告)

Long-term Results Analysis For Complex Treatment of Breast Cancer

１９８１～１９８３年有７０２例乳腺癌接受了根治手术和化疗，有／无术后放疗。Ⅰ期８３例，Ⅱ期３９０例，Ⅲ期２２９例。根治术４７１例，改良根治２０４例，２７例行全乳切除加低位腋清除术。所有病人都接受了全身化疗和有选择的区域放疗。Ⅰ、Ⅱ、Ⅲ期１０年生存率分别为８０．５％、６２．５％、５１．８％。好于其他作者和我们过去的报导。回顾分析的结论为：综合治疗乳腺癌改善了远期生存率，对腋淋巴结阳性患者补加术后放疗降低了锁上复发率，但没有看到术后放疗对预后的明显影响。

Purpose:To analyse survivsl status of patients with breast cancer treated by complex management and edtermine the factors influencing the prognosis. Material and Methods:From 1981 to 1983, 702 cases of breast cancer received mastectomy combined with chemotherapy and/or postoperative radiotherapy. There are 83 cases StageI, 390 StageⅡ and 229 StageⅢ. 471 patients underwent radical mastectomy, 204 patients underwent modified mastectomy, and 27 patients underwent total mastectomy with low axillary nodes resection.All patients were given system chemotherapy and selective regional radiation.Results:10-year survival rate were 80.5%、62.5%、51.8% respectively for stage Ⅰ、Ⅱ、Ⅲ. This results is better than of previouslg reported.Conclusion:Long-term survival of breast cancer is improved with the complex modalities.Postmastectomy radiotherapy reduces supervascular recur rence for patients with axillary node positive. But it has no significant influence of prognosis in this retrospectively study.