宫颈电环切术对妊娠时限及分娩方式的影响

The Effect of Loop Electrosurgical Excision on Pregnancy Duration and Mode of Delivery

目的:探讨宫颈上皮内瘤变患者行宫颈电环切术对妊娠时限、分娩方式及新生儿情况的影响。方法:选择因宫颈上皮内瘤变而行宫颈电环切术,于术后妊娠并分娩的32例产妇为研究组,同时取同期分娩且孕前未行任何宫颈手术的产妇64例为对照组,观察两组间的妊娠时限、分娩方式及新生儿出生体重等指标的差异。结果:两组资料可比性强。研究组早产3例,剖宫产16例,2例新生儿出生体重<2500g。对照组早产7例,剖宫产30例,6例新生儿出生体重<2500g。两组间早产率、剖宫产率、低出生体重儿率差异均无显著性(P>0.05)。结论:宫颈电环切术是治疗宫颈上皮内瘤变安全有效的方法,不会增加随后妊娠的剖宫产率、早产率和低出生体重儿率。

Objective：To investigate the effect of loop electrosurgical excision procedure（LEEP） on duration of pregnancy, mode of delivery and neonatal outcomes of patients with cervical intraepithelial neoplasia （CIN）. Methods：A retrospective cohort study was performed. The study group enrolled 32 women, who gave birth after previous LEEP treatment for CIN. The control group had 64 women with no history of cervical surgery, who delivered within the same period. The duration of pregnancy, mode of delivery and neonatal outcomes were analyzed.Results：The numbers of preterm birth, cesarean delivery and low birth weight in study group are 3, 16, 2 cases respectively. While in control group, numbers were 7, 30, and 6 respectively. Duration of pregnancy, incidence of preterm birth and low birth weight were not significantly different between the two groups （ P〉 0.05） .Conclusions= LEEP is a safe and effective treatment for CIN. It does not increase the risk of cesarean delivery, preterm birth or low birth weight infant.