药源性急性胰腺炎及其相关药物

Drug-induced Acute Pancreatitis and Related Drugs

药源性急性胰腺炎是药物诱发的一种医源性消化道急症。药源性急性胰腺炎尽管比较少见,但为了提高临床用药安全性,应加强对药源性急性胰腺炎临床表现及相关药物的监测。现就利尿药、甾体类激素、非甾体类抗炎药物、抗菌药物、抗肿瘤药物、中枢神经系统药物、心血管药物、中草药等10余种药物诱发的胰腺炎的发病机制、罹病药物、临床表现及诊断治疗要点等进行阐述。

As one of iatrogenic acute gastrointestinal complications, drug-induced acute panereatitis （DAP） is not seen commonly, whose manifestations should he carefully observed for the safety of drug administration.This review was focused on the mechanisms,clinical manifestations,diagnosis and treatment of DAP induced by various drugs, including diuretics, steroid hormones, non-steroidal anti-inflammatory drugs, antibiotics, anticancer drugs, central nervous system drugs, cardiovascular drugs,herbs, and so forth.