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2-氨基喹唑啉类化合物的合成 被引量：2

Synthesis of 2-aminoquinazoline derivatives
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摘要 2-氨基喹唑啉类化合物是一类具有多种生物活性的含氮杂环化合物,综述了其主要合成方法,并进行了简要的评述。 The procedure for preparation, test and certification of water quality certified reference material titanium （Ti） was developed after performing the study on stability and homogeneity assessment and concentration of the relevant samples. The research result showed that the water quality certified reference material titanium （Ti） had excellent homogeneity and should be stable at least for one and a haft years with trustable certified concentration value.
作者 赵保丽 曹胜利
机构地区 首都师范大学化学系
出处 《化学试剂》 CAS CSCD 北大核心 2008年第3期181-184,196,共5页 Chemical Reagents
关键词 喹唑啉 合成 综述 titanium （Ti） environment certified reference material
分类号 O626 [理学—有机化学]
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参考文献23

  • 1ASHTON W T, HYNES J B. Synthesis of 5-substituted quinazolines as potential antimalarial agents[J]. J. Med. Chem. , 1973,16(11) :1233-1237.
  • 2DAVOLL J, JOHNSON A M. Quinazoline analogues of folic acid[J]. J. Chem. Soc. (C), 1970,8:997-1002.
  • 3ROSOWSKY A, MARINI J L, MADEL M E, et al. Quinazolines. Ⅵ. synthesis of 2, 4-diaminoquinazolines from anthranilonitrles[ J]. J. Med. Chem., 1970,13 (5) : 882-886.
  • 4HYNES J B, PATHAK A, PANOS C H, et al. Direct synthesis of 2,4-diaminoquinazolines from 2-fluorobenzonitriles [ J ]. J. Heterocycl. Chem. ,1988,.7,5:1173-1177.
  • 5WERBEL L M, ELSLAGER E F, NEWTON L S. Synthesis and antimalarial activity of a series of 2,4-diamino-6-[ (N- alkyanilino) methyl ] quinazolines [ J ]. J . Heterocycl . Chem., 1987,24(2) :345-349.
  • 6OAKES V, RYDON H N, UNDHEIM K. Polyazanaph- thalenes. Part Ⅶ . some derivatives of quinazoline and 1, 3,5- triazanaphthalene[ J] . J . Chem. Soc . , 1962:4678-4685.
  • 7SU T L, HUANG J T, BURCHENAL J H, et al. Synthesis and biological activities of 5-deaza analogues of aminopterin and folic acid[J]. J . Med . Chem. , 1986,29(5) :709-715.
  • 8ROSOWSKY A, FORSCH R A, QUEENER S F. 2, 4-Diaminopyrido [ 3,2- d ] pyrimidine inhibitors of dihydrofolate reductase from pneumocystis carinii and toxoplasma gondii[J]. J. Med. Chem. ,1995,38(14):2 615-2 620.
  • 9SRINIVASAN A, BROOM A D. Pyridopyrimidines. 12. synthesis of 8-deaza analogues of aminopterin and folic acid[J]. J. Org. Chem., 1981,46(9) : 1777-1781.
  • 10HYNES J B, CAMPBELL J P, HYNES J D. Synthesis of 2-aminoquinazolines from ortho-fluoroketones [ J ]. J. Heterocycl. Chem ,1995,32:1185-1187.

同被引文献16

  • 1杨松,刘刚,宋宝安,金林红,胡德禹,张素梅.4-(N-取代苯基)氨基喹唑啉类化合物的合成及抗磷酸化活性研究[J].有机化学,2006,26(10):1429-1433. 被引量：9
  • 2张洋,马玉卓,刘鹰翔.4-(4′-羟基苯基)-氨基-6,7-二甲氧基喹唑啉的合成[J].化学试剂,2007,29(2):109-110. 被引量：4
  • 3Curd F H S, Landquist J K, Rose F L. Synthetic antimalarials Part XIV. Some [J]. J Chem Soc, 2 -arylamino -4-1947: 775-783.
  • 4Xu G, Song B, Bhadury P S, et al. Synthesis and antifungal activity of novel 6-fluoro-4-alkyl (aryl)thioquinazoline derivatives [J]. Bioorg Med Chem, 2007, 15(11 ) : 3 768-3 774.
  • 5Alagarsamy V, salomon V R, Vanikavitha G, et al. Synthesis, analgesic, anti-inflammatory and antibacterial activities of some novel 2-phenyl-3-substitued quinazolin-4 (3H)ones [J]. Biol Pharm Bull, 2002, 25(11 ) : 1 432-1 435.
  • 6Hayao S, Havera H J, Strycker W G, et al. New sedative and hypotensive 3-substitued-2,4 (1H,3H)-quinazolines [J]. J Med Chem, 1965, 8: 807-811.
  • 7Ei-Brollosy N R. Synthesis of new quinazoline-2,4-( 1H, 3H)dione non-nucleoside analogues of the reverse transcriptase inhibitor TNK-651 [J]. J Chem Res, 2007 : 358-361.
  • 8Lokker N A, Sullivan C M, Hollenbach S J, et at. Plateletderived growth factor (PDGF)autoerine signaling regulates survival and mitogenie pathways in glioblastoma cells: Evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors [J]. CancerRes, 2002, 62 (13) : 3 729-3 735.
  • 9刘刚,李晓燕.喹唑啉类化合物生物活性研究进展[J].药学进展,2007,31(12):542-550. 被引量：10
  • 10张向阳,刘章琴,陈元伟.新型喹唑啉类酪氨酸激酶化学抑制剂的设计与合成[J].合成化学,2009,17(2):199-202. 被引量：2

引证文献2

化学试剂
2008年 第3期

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