前列化浊胶囊治疗湿热瘀滞型慢性前列腺炎的临床观察

Effect of Qianlie Huazhuo Capsule for Treatment of Chronic Prostatitis of Dampness-heat Stagnancy Type

目的观察前列化浊胶囊对湿热瘀滞型慢性前列腺炎患者的疗效。方法选择湿热瘀滞型慢性前列腺炎患者65例,随机分为两组,分别用前列化浊胶囊(治疗组)和前列解毒胶囊(对照组)治疗,疗程为1个月,在治疗前及治疗的第4周末进行慢性前列腺炎NIH-CPSI评分,并行SF-12量表评定。结果治疗组32例,治愈2例,显效15例,有效9例,无效6例,总有效率81.2%;对照组33例,治愈2例,显效5例,有效13例,无效13例,总有效率60.6%,两组总有效率比较差异有统计学意义(P<0.05);NIH-CPSI生活质量评分治疗组较对照组显著下降(P<0.05);SF-12体能组成量表(躯体不适感)总得分治疗组较对照组改善明显(P<0.05),SF-12智能组成量表(精神方面)总得分两组比较差异无统计学意义。结论前列化浊胶囊治疗湿热瘀滞型慢性前列腺炎疗效较好。

Objective To evaluate the therapeutic effects of Qianlie Huazhuo Capsule （QHC） on patients with chronic prostatitis of dampness-heat stagnancy type （CP-DHS）. Methods Sixty-five patients were randomly assigned to the treatment group （32 cases） treated with QHC and the control group （33 cases） treated with Qianlie Jiedu Capsule, for 1 month respectively. The clinical efficacy was evaluated at the end of the 2nd and 4th month, their quality of life （QOL） was estimated by NIH Chronic Prostatitis Syndrome Index （NIH-CPSI） and patients＇ capacity was estimated by SF-12 scale as well. Results Out of patients in the treatment group, 2 got cured, notable effect showed in 15, effective in 9, and ineffective in 6, the total effective rate being 81.2% , while in the 33 patients of the control group, 2 got cured, notable effect in 5, effective in 13 and ineffective in 13, the total effective rate 60.6%, the difference between the two groups was statistically significant in the total efficacy （ P 〈 0.05 ）. As compared with the control group, the NIH-CPSI score for QOL was significantly lower, SF-12 physical capacity score was better in the treatment group （both P 〈 0. 05）, and SF-12 mental capacity score in the two groups showed insignificant difference. Conclusion QHC could obtain good effect for the treatment of CP-DHS.