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纳洛酮治疗肝性脑病28例疗效观察 被引量:2

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摘要 目的观察纳洛酮治疗肝性脑病的疗效。方法将52例肝性脑病患者随机分为治疗组(28例)和对照组(24例),对照组仅用综合基础治疗;治组在此基础上加用纳洛酮0.8mg,每6~8h一次。结果治疗组总有效率89.3%,对照组总有效率58.3%;两组清醒后的血氨水平均较清醒前明显下降,且以治疗组更为明显(P〈0.01),且治疗组血氨水平下降程度较对照组大;两组患者神志清醒时间,治疗组为(62.26±9.35)min,短于对照组(195.25±10.20)min;治疗组的病死率低于对照组的,两组比较差异均有有统计学意义(P〈0.01)。结论纳洛酮是治疗肝性脑病的有效药物,值得临床推广。
出处 《广东医学院学报》 2008年第1期47-48,共2页 Journal of Guangdong Medical College
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